The Effect of Anticonvulsants on Bone Mineral Density: Brief Review
https://doi.org/10.52667/2712-9179-2023-3-2-32-37
Abstract
The effect of anticonvulsants on bone mineral density changes in epileptic patients is an important and relevant scientific question. This brief review focuses on assessing the existing knowledge on how antiepileptic drugs affect bone mineral density. The review examines the various mechanisms that may influence bone mineral density when anticonvulsants are taken. Based on a literature search and analysis, advances in the field are identified and their contribution to the current understanding of the issue is assessed. Overall, this review can serve as an informative resource for understanding the relationship between antiepileptic drugs and bone mineral density and as a direction for future research.
Keywords
epilepsy,
bone mineral density,
osteoporosis,
osteopenia,
densitometry,
antiepileptic drugs,
anticonvulsants
Supporting agencies: Supported by Russian Science Foundation № 23-25-00104, https://rscf.ru/en/project/23-25-00104
About the Authors
N. A. Sivakova
V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology
Russian Federation
Russian Federation
Natalia A. Sivakova
192019 St. Petersburg
Tel.: 8 (812) 670-02-20
I. V. Abramova
V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology
Russian Federation
Russian Federation
Irina V. Abramova
192019 St. Petersburg
V. P. Rybasova
V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology
Russian Federation
Russian Federation
Varvara P. Rybasova
192019 St. Petersburg
I. Yu. Trukhina
V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology
Russian Federation
Russian Federation
Irina Yu. Trukhina
192019 St. Petersburg
L. V. Lukina
V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology
Russian Federation
Russian Federation
Larisa V. Lukina
192019 St. Petersburg
R. F. Nasyrova
V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology
Russian Federation
Russian Federation
Regina F. Nasyrova
192019 St. Petersburg
V. A. Mikhailov
V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology
Russian Federation
Russian Federation
Vladimir A. Mikhailov
192019 St. Petersburg
G. E. Mazo
V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology
Russian Federation
Russian Federation
Galina E. Mazo
192019 St. Petersburg
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Review
For citations:
Sivakova N.A., Abramova I.V., Rybasova V.P., Trukhina I.Yu., Lukina L.V., Nasyrova R.F., Mikhailov V.A., Mazo G.E. The Effect of Anticonvulsants on Bone Mineral Density: Brief Review. Personalized Psychiatry and Neurology. 2023;3(2):32-37. https://doi.org/10.52667/2712-9179-2023-3-2-32-37
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