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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">ppan</journal-id><journal-title-group><journal-title xml:lang="en">Personalized Psychiatry and Neurology</journal-title><trans-title-group xml:lang="ru"><trans-title>Personalized Psychiatry and Neurology</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2712-9179</issn><publisher><publisher-name>V. M. Bekhterev National Medical Research Centre for Psychiatry and Neurology of the Ministry of Health of the Russian Federation (Bekhterev NMRC PN)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52667/2712-9179-2023-3-2-32-37</article-id><article-id custom-type="elpub" pub-id-type="custom">ppan-82</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>The Effect of Anticonvulsants on Bone Mineral Density: Brief Review</article-title><trans-title-group xml:lang="ru"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Sivakova</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="en"><p>Natalia A. Sivakova</p><p>192019 St. Petersburg</p><p>Tel.: 8 (812) 670-02-20</p></bio><email xlink:type="simple">dr.sivakovan@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Abramova</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="en"><p>Irina V. Abramova</p><p>192019 St. Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Rybasova</surname><given-names>V. P.</given-names></name></name-alternatives><bio xml:lang="en"><p>Varvara P. Rybasova</p><p>192019 St. Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Trukhina</surname><given-names>I. Yu.</given-names></name></name-alternatives><bio xml:lang="en"><p>Irina Yu. Trukhina</p><p>192019 St. Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Lukina</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="en"><p>Larisa V. Lukina</p><p>192019 St. Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Nasyrova</surname><given-names>R. F.</given-names></name></name-alternatives><bio xml:lang="en"><p>Regina F. Nasyrova</p><p>192019 St. Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Mikhailov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="en"><p>Vladimir A. Mikhailov</p><p>192019 St. Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Mazo</surname><given-names>G. E.</given-names></name></name-alternatives><bio xml:lang="en"><p>Galina E. Mazo</p><p>192019 St. Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="en">V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>15</day><month>11</month><year>2023</year></pub-date><volume>3</volume><issue>2</issue><fpage>32</fpage><lpage>37</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Sivakova N.A., Abramova I.V., Rybasova V.P., Trukhina I.Y., Lukina L.V., Nasyrova R.F., Mikhailov V.A., Mazo G.E., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Sivakova N.A., Abramova I.V., Rybasova V.P., Trukhina I.Y., Lukina L.V., Nasyrova R.F., Mikhailov V.A., Mazo G.E.</copyright-holder><copyright-holder xml:lang="en">Sivakova N.A., Abramova I.V., Rybasova V.P., Trukhina I.Y., Lukina L.V., Nasyrova R.F., Mikhailov V.A., Mazo G.E.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.jppn.ru/jour/article/view/82">https://www.jppn.ru/jour/article/view/82</self-uri><abstract><p>The effect of anticonvulsants on bone mineral density changes in epileptic patients is an important and relevant scientific question. This brief review focuses on assessing the existing knowledge on how antiepileptic drugs affect bone mineral density. The review examines the various mechanisms that may influence bone mineral density when anticonvulsants are taken. Based on a literature search and analysis, advances in the field are identified and their contribution to the current understanding of the issue is assessed. Overall, this review can serve as an informative resource for understanding the relationship between antiepileptic drugs and bone mineral density and as a direction for future research.</p></abstract><kwd-group xml:lang="en"><kwd>epilepsy</kwd><kwd>bone mineral density</kwd><kwd>osteoporosis</kwd><kwd>osteopenia</kwd><kwd>densitometry</kwd><kwd>antiepileptic drugs</kwd><kwd>anticonvulsants</kwd></kwd-group><funding-group xml:lang="en"><funding-statement>Supported by Russian Science Foundation № 23-25-00104, https://rscf.ru/en/project/23-25-00104</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Meena, U.K.; Meena, D.S.; Behera, P.; Meel, O.S. Bilateral central acetabular fracture dislocation in a young patient due to seizure activity: a case report and review of the literature. Chinese Journal of Traumatology. 2014; 17(6): 364-366. 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