ppanPersonalized Psychiatry and NeurologyPersonalized Psychiatry and Neurology2712-9179V. M. Bekhterev National Medical Research Centre for Psychiatry and Neurology of the Ministry of Health of the Russian Federation (Bekhterev NMRC PN)10.52667/10.52667/2712-9179-2024-4-1-2-17-9179-2024-4-1-32-40ppan-95Research ArticleCASE REPORTAtypical Structure of Broca's Area in a Patient with Primary Progressive Atrophy Syndrome at the Onset of Alzheimer's DiseaseKotsiubinskayaYu. V.

Yulia V. Kotsiubinskaya

192019, Saint Petersburg

VasilevV. V.

Vladimir V. Vasilev

192019, Saint Petersburg

KazakovA. V.

Anton V. Kazakov

192019, Saint Petersburg

StulovI. K.

Ilya K. Stulov

192019, Saint Petersburg

MikhailovV. A.

Vladimir A. Mikhailov

192019, Saint Petersburg

V.M. Bekhterev National Medical Research Centre for Psychiatry and NeurologyRussian Federation202425032024413240Copyright © Kotsiubinskaya Y.V., Vasilev V.V., Kazakov A.V., Stulov I.K., Mikhailov V.A., 20242024Kotsiubinskaya Y.V., Vasilev V.V., Kazakov A.V., Stulov I.K., Mikhailov V.A.Kotsiubinskaya Y.V., Vasilev V.V., Kazakov A.V., Stulov I.K., Mikhailov V.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.jppn.ru/jour/article/view/95

This article presents a clinical case of Alzheimer’s disease with a debut as primary progressive aphasia syndrome. Insufficient use of routine magnetic resonance imaging in this case in the diagnosis of neurodegenerative diseases and the advantage of such additional neuroimaging methods as positron emission tomography, functional magnetic resonance imaging with a scale assessment of atrophic changes. Additional neuroimaging techniques have been shown to significantly improve the early detection of pathological changes in brain structures and to reveal the location of functional areas involved in the neurodegenerative process.

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The authors declare that there are no conflicts of interest present.