ppanPersonalized Psychiatry and NeurologyPersonalized Psychiatry and Neurology2712-9179V. M. Bekhterev National Medical Research Centre for Psychiatry and Neurology of the Ministry of Health of the Russian Federation (Bekhterev NMRC PN)10.52667/2712-9179-2022-2-1-57-66ppan-39Research ArticleREVIEWEpidemiology of Amyotrophic Lateral SclerosisGoncharovaP. S.

Polina S. Goncharova

92019, St.-Petersburg; tel.: +79536283842

po.gon4arova@yandex.ruDavidovaT. K.

Tatiana K. Davidova

677000, Yakutsk

ShnayderN. A.

Natalia A. Shnayder

192019, St.-Petersburg; 660022, Krasnoyarsk

NovitskyM. A.

Maxim A. Novitsky

192019, St.-Petersburg

NasyrovaR. F.

Regina F. Nasyrova 

192019, St.-Petersburg

V.M. Bekhterev National Medical Research Centre for Psychiatry and NeurologyRussian FederationYakut Science Centre of Complex Medical ProblemsRussian FederationV.M. Bekhterev National Medical Research Centre for Psychiatry and Neurology; V.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityRussian Federation202215052022215766Copyright © Goncharova P.S., Davidova T.K., Shnayder N.A., Novitsky M.A., Nasyrova R.F., 20222022Goncharova P.S., Davidova T.K., Shnayder N.A., Novitsky M.A., Nasyrova R.F.Goncharova P.S., Davidova T.K., Shnayder N.A., Novitsky M.A., Nasyrova R.F.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.jppn.ru/jour/article/view/39

We searched for full-text publications in Russian and English in the E-Library, PubMed, Springer, Clinical keys, Google Scholar databases, using keywords and combined word searches (amyotrophic lateral sclerosis - ALS, motor neuron disease, epidemiology, incidence, prevalence), for 2015 – 2020. In addition, the review included earlier publications of historical interest. Despite our comprehensive searches of these commonly used databases and search terms, it cannot be excluded that some publications may have been missed. A total of 74 publications were analyzed, reflecting epidemiological studies of ALS in 168 countries. The incidence of ALS worldwide varies from 0.4 per 100,000 per year (Ecuador) to 9.45 per 100,000 per year (Japan, Oshima region). Prevalence - from 0.1 per 100,000 population (Somalia) to 42.1 per 100,000 population (Canada). This data depends on many factors, including the quality of the diagnosis and the health care system.

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The authors declare that there are no conflicts of interest present.