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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">ppan</journal-id><journal-title-group><journal-title xml:lang="en">Personalized Psychiatry and Neurology</journal-title><trans-title-group xml:lang="ru"><trans-title>Personalized Psychiatry and Neurology</trans-title></trans-title-group></journal-title-group><issn pub-type="epub">2712-9179</issn><publisher><publisher-name>V. M. Bekhterev National Medical Research Centre for Psychiatry and Neurology of the Ministry of Health of the Russian Federation (Bekhterev NMRC PN)</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ppan-26</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ARTICLE</subject></subj-group></article-categories><title-group><article-title>Efficiency and safety of the author's method of wrist tapping as a personalized method of emergency self-help in focal epilepsy</article-title><trans-title-group xml:lang="ru"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Narodova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="en"><p>Ekaterina A. Narodova</p><p>660022, Krasnoyarsk</p></bio><email xlink:type="simple">katya_n2001@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Narodova</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="en"><p>Valeria V. Narodova</p><p>660022, Krasnoyarsk</p></bio><email xlink:type="simple">narodova_v@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Petrov</surname><given-names>K. V.</given-names></name></name-alternatives><bio xml:lang="en"><p>Kirill V. Petrov</p><p>660022, Krasnoyarsk</p></bio><email xlink:type="simple">kllpetrov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Yakunina</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="en"><p>Albina V. Yakunina</p><p>443099, Samara</p></bio><email xlink:type="simple">ayakunina@bk.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Poverennova</surname><given-names>I. E.</given-names></name></name-alternatives><bio xml:lang="en"><p>Irina E. Poverennova</p><p>443099, Samara</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="en" id="aff-1"><institution>Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University</institution><country>Russian Federation</country></aff><aff xml:lang="en" id="aff-2"><institution>Samara State Medical University</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>14</day><month>11</month><year>2021</year></pub-date><volume>1</volume><issue>2</issue><fpage>106</fpage><lpage>110</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Narodova E.A., Narodova V.V., Petrov K.V., Yakunina A.V., Poverennova I.E., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Narodova E.A., Narodova V.V., Petrov K.V., Yakunina A.V., Poverennova I.E.</copyright-holder><copyright-holder xml:lang="en">Narodova E.A., Narodova V.V., Petrov K.V., Yakunina A.V., Poverennova I.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.jppn.ru/jour/article/view/26">https://www.jppn.ru/jour/article/view/26</self-uri><abstract><p>Currently, a search for a solution to the problem of drug-resistant epilepsy is being actively pursued. Along with personalized (including targeted) drug methods, personalized nondrug methods of treating drug-resistant epilepsy are being actively developed. Our previous studies have shown that the developed author's technique with an individual selection of the wrist tapping (WT) leads to an increase in the activity of the frontotemporal cortex, mainly of the right hemisphere, involved in emotional control, and a decrease in the fear of recurrence of focal epileptic seizures (FS) or transformation of FS into bilateral tonic-clonic seizures (BTCS). In addition, WT leads to a decrease in intrahemispheric coherence in the frontotemporal regions of the left hemisphere, which is a biomarker for reducing the risk of generalized epileptic activity.</p></abstract><kwd-group xml:lang="en"><kwd>epilepsy</kwd><kwd>drug-resistant</kwd><kwd>epileptic seizure</kwd><kwd>personalized therapy</kwd><kwd>wrist tapping</kwd><kwd>EpiTapp</kwd><kwd>efficacy</kwd><kwd>safety</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Shnayder, N.A., Narodova, E.A., Narodova, V.V., Dmitrenko, D.V., Artyukhov, I.P. The Role of Nondrug Treatment Methods in the Management of Epilepsy. International Journal of Biomedicine 2018, 8(1), 9-14. DOI:10.21103/Article8(1)_BR</mixed-citation><mixed-citation xml:lang="en">Shnayder, N.A., Narodova, E.A., Narodova, V.V., Dmitrenko, D.V., Artyukhov, I.P. The Role of Nondrug Treatment Methods in the Management of Epilepsy. International Journal of Biomedicine 2018, 8(1), 9-14. DOI:10.21103/Article8(1)_BR</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Narodova, E.A., Shnayder, N.A., Karnaukhov, V.E., Petrov, K.V., Narodova, V.V. Influence of Wrist Tapping on Alpha Rhythm Synchronization in Patients with Juvenile Myoclonic Epilepsy. International Journal of Biomedicine 2020, 10(4), 347 –351. DOI:10.21103/Article10(4)_OA3</mixed-citation><mixed-citation xml:lang="en">Narodova, E.A., Shnayder, N.A., Karnaukhov, V.E., Petrov, K.V., Narodova, V.V. Influence of Wrist Tapping on Alpha Rhythm Synchronization in Patients with Juvenile Myoclonic Epilepsy. International Journal of Biomedicine 2020, 10(4), 347 –351. DOI:10.21103/Article10(4)_OA3</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Narodova, E.A., Shnayder, N.A., Karnaukhov, V.E., Petrov, K.V., Narodova, V.V. Study of the influence of Wrist tapping on alpha-rhythm synchronization in adults. Archiv euromedica 2020, 10(4), 118-123. DOI: 10.35630/2199-885X/2020/10/4.28</mixed-citation><mixed-citation xml:lang="en">Narodova, E.A., Shnayder, N.A., Karnaukhov, V.E., Petrov, K.V., Narodova, V.V. Study of the influence of Wrist tapping on alpha-rhythm synchronization in adults. Archiv euromedica 2020, 10(4), 118-123. DOI: 10.35630/2199-885X/2020/10/4.28</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Vollmar, C., O'Muircheartaigh, J., Barker, G.J., Symms, M.R., Thompson, P., Kumari, V., Duncan, J.S., Janz, D., Richardson, M.P., Koepp, M.J. Motor system hyperconnectivity in juvenile myoclonic epilepsy: a cognitive functional magnetic resonance imaging study. Brain 2011, 134(6), 1710-1719. DOI:10.1093/brain/awr098</mixed-citation><mixed-citation xml:lang="en">Vollmar, C., O'Muircheartaigh, J., Barker, G.J., Symms, M.R., Thompson, P., Kumari, V., Duncan, J.S., Janz, D., Richardson, M.P., Koepp, M.J. Motor system hyperconnectivity in juvenile myoclonic epilepsy: a cognitive functional magnetic resonance imaging study. Brain 2011, 134(6), 1710-1719. DOI:10.1093/brain/awr098</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Narodova, E.A., Rudnev, V.A., Shnayder, N.A., Narodova, V.V., Erakhtin, E.E., Dmitrenko, D.V., Shilkina, O.S., Moscaleva, P.V., Gazenkampf, K.A. Parameters of the Wrist Tapping using a Modification of the Original Method (Method of exogenous rhythmic stimulation influence on an individual human rhythm). International Journal of Biomedicine 2018, 8(2), 155– 158. DOI: 10.21103/Article8(2)_OA10</mixed-citation><mixed-citation xml:lang="en">Narodova, E.A., Rudnev, V.A., Shnayder, N.A., Narodova, V.V., Erakhtin, E.E., Dmitrenko, D.V., Shilkina, O.S., Moscaleva, P.V., Gazenkampf, K.A. Parameters of the Wrist Tapping using a Modification of the Original Method (Method of exogenous rhythmic stimulation influence on an individual human rhythm). International Journal of Biomedicine 2018, 8(2), 155– 158. DOI: 10.21103/Article8(2)_OA10</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
