Phytotherapy, as a traditional medicine method, has diverse therapeutic properties that can be used for disease-modifying therapy of intervertebral disc degeneration (IDD) in humans. Of particular interest are herbal remedies for the correction of chronic inflammation (primarily cytokine imbalance). The aim of this descriptive review is to update knowledge about herbal methods that are promising or traditionally used for the correction of cytokine imbalance in IDD. The results of preclinical and clinical studies and publications of historical interest on the traditional use of herbal remedies in Eastern and Western medicine were analyzed. Most herbal remedies for the correction of cytokine imbalance in IDD have evidence classes C and D, while the number of herbal remedies with evidence classes A and B is still small, despite many years and even centuries of experience in traditional medicine. In recent decades, there has been a trend toward increased research interest in this topic, with a growing number of preclinical studies of herbal remedies in animal models of IDD and arthritis (including arthritis of the facet joints of the spine). This review has demonstrated that traditional herbal medicine has not lost its clinical significance and can be used as a component of disease-modifying therapy for IDD in humans. Planning and conducting new preclinical and clinical studies of herbal remedies for this disease are necessary to increase the level of evidence for their use in clinical practice in accordance with modern requirements.